L-Histidine hydrochloride monohydrate is a salt form of L-histidine, an α-amino acid that plays an important role in various biological processes. It is used as a dietary supplement, a pharmaceutical ingredient, and a component in cell culture media. Uses Nutritional supplement: L-Histidine hydrochloride can be used to treat histidine deficiency in individuals with inadequate dietary intake or certain medical conditions. Supportive therapy: It can be part of intravenous nutrition for critically ill patients to aid in tissue repair and recovery. Research and development: L-histidine hydrochloride is utilized in metabolic studies and biochemical research. Protein Stabilization: It enhances the stability of monoclonal antibodies (mAbs) during manufacturing, due to its buffering capacity, metal ion chelation properties, and ability to improve protein solubility. Anemia Management: It can aid in managing anemia by promoting hemoglobin synthesis. Benefits Supports muscle repair and immune function Improves wound healing and recovery Aids in maintaining pH balance in the body Essential in infants and patients under metabolic stress Precautions and side effects Consult a healthcare professional before taking L-histidine hydrochloride, especially during pregnancy or while breastfeeding. Possible side effects: Nausea, headache, mild allergic reactions. Excessive consumption: May lead to adverse reactions or allergies, including lower folic acid levels and increased zinc loss. Folic acid deficiency: Individuals with folic acid deficiency should avoid histidine